PUBLICATIONS RESEARCH AREA C

Project C1

  • Braaß H, Feldheim J, Chu Y, Tinnermann A, Finsterbusch J, Büchel C, Schulz R, Gerloff C (2023a) Association between activity in the ventral premotor cortex and spinal cord activation during force generation. Hum Brain Mapp 44: 6471-6483. DOI: 10.1002/hbm.26523
  • Braaß H, Gutgesell L, Backhaus W, Higgen FL, Quandt F, Choe C, Gerloff C, Schulz R (2023b) Early functional connectivity alterations in contralesional motor networks influence outcome after severe stroke: a preliminary analysis. Sci Rep 13: 11010. DOI: 10.1038/s41598-023-38066-0
  • Guder S, Sadeghi F, Zittel S, Quandt F, Choe C, Bönstrup M, Cheng B, Thomalla G, Gerloff C, Schulz R (2023) Disability and persistent motor deficits are linked to structural crossed cerebellar diaschisis in chronic stroke. Hum Brain Mapp 44: 5336-5345. DOI: 10.1002/hbm.26434
  • Wróbel PP, Guder S, Feldheim JF, Graterol Pérez JA, Frey BM, Choe C, Bönstrup M, Cheng B, Rathi Y, Pasternak O, Thomalla G, Gerloff C, Shenton ME, Schulz R (2023) Altered microstructure of the contralesional ventral premotor cortex and motor output after stroke. Brain Commun 5: fcad160. DOI: 10.1093/braincomms/fcad160
  • Graterol Pérez JA, Guder S, Choe C, Gerloff C, Schulz R (2022) Relationship between cortical excitability changes and cortical thickness in subcortical chronic stroke. Front Neurol 13: 802113. DOI: 10.3389/fneur.2022.802113
  • Rojas Albert A, Backhaus W, Graterol Pérez JA, Braaβ H, Schön G, Choe C, Feldheim J, Bönstrup M, Cheng B, Thomalla G, Gerloff C, Schulz R (2022) Cortical thickness of contralesional cortices positively relates to future outcome after severe stroke. Cereb Cortex 32: 5622-5627. DOI: 10.1093/cercor/bhac040
  • Sadeghihassanabadi F, Frey BM, Backhaus W, Choe CU, Zittel S, Schön G, Bönstrup M, Cheng B, Thomalla G, Gerloff C, Schulz R (2022) Structural cerebellar reserve positively influences outcome after severe stroke. Brain Commun 4: fcac203. DOI: 10.1093/braincomms/fcac203
  • Backhaus W, Braaß H, Higgen FL, Gerloff C, Schulz R (2021) Early parietofrontal network upregulation relates to future persistent deficits after severe stroke-a prospective cohort study. Brain Commun 3: fcab097. DOI: 10.1093/braincomms/fcab097
  • Guder S, Pasternak O, Gerloff C, Schulz R (2021) Strengthened structure-function relationships of the corticospinal tract by free water correction after stroke. Brain Commun 3: fcab034. DOI: 10.1093/braincomms/fcab034
  • Schulz R, Bönstrup M, Guder S, Liu J, Frey B, Quandt F, Krawinkel LA, Cheng B, Thomalla G, Gerloff C (2021) Corticospinal tract microstructure correlates with beta oscillatory activity in the primary motor cortex after stroke. Stroke 52: 3839-3847. DOI: 10.1161/STROKEAHA.121.034344
  • Wolf S, Gerloff C, Backhaus W (2021) Predictive value of upper extremity outcome measures after stroke – a systematic review and metaregression analysis. Front Neurol 12: 675255. DOI: 10.3389/fneur.2021.675255
  • Guder S, Frey BM, Backhaus W, Braass H, Timmermann JE, Gerloff C, Schulz R (2020) The influence of cortico-cerebellar structural connectivity on cortical excitability in chronic stroke. Cereb Cortex 30: 1330-1344. DOI: 10.1093/cercor/bhz169
  • Nemati PR, Backhaus W, Feldheim J, Bönstrup M, Cheng B, Thomalla G, Gerloff C, Schulz R (2022) Brain network topology early after stroke relates to recovery. Brain Commun 4: fcac049. DOI: 10.1093/braincomms/fcac049
  • Quandt F, Fischer F, Schröder J, Heinze M, Kessner SS, Malherbe C, Schulz R, Cheng B, Fiehler J, Gerloff C, Thomalla G (2020a) Normalization of reduced functional connectivity after revascularization of asymptomatic carotid stenosis. J Cereb Blood Flow Metab 40:1838-1848. DOI: 10.1177/0271678X19874338
  • Quandt F, Fischer F, Schröder J, Heinze M, Lettow I, Frey BM, Kessner SS, Schulz M, Higgen FL, Cheng B, Gerloff C, Thomalla G (2020b) Higher white matter hyperintensity lesion load is associated with reduced long-range functional connectivity. Brain Commun 2: fcaa111. DOI: 10.1093/braincomms/fcaa111
  • Schlemm E, Schulz R, Bönstrup M, Krawinkel L, Fiehler J, Gerloff C, Thomalla G, Cheng B (2020) Structural brain networks and functional motor outcome after stroke-a prospective cohort study. Brain Commun 2: fcaa001. DOI: 10.1093/braincomms/fcaa001
  • Bönstrup M, Krawinkel L, Schulz R, Cheng B, Feldheim J, Thomalla G, Cohen LG, Gerloff C (2019) Low-frequency brain oscillations track motor recovery in human stroke. Ann Neurol 86: 853-865. DOI: 10.1002/ana.25615
  • Finger H, Gast R, Gerloff C, Engel AK, König P (2019) Probing neural networks for dynamic switches of communication pathways. PLoS Comput Biol 15: e1007551. DOI: 10.1371/journal.pcbi.1007551
  • Cheng B, Schlemm E, Schulz R, Boenstrup M, Messé A, Hilgetag C, Gerloff C, Thomalla G (2019) Altered topology of large-scale structural brain networks in chronic stroke. Brain Commun 1: fcz020. DOI: 10.1093/braincomms/fcz020

  • Bönstrup M, Schulz R, Schön G, Cheng B, Feldheim J, Thomalla G, Gerloff C (2018) Parietofrontal network upregulation after motor stroke. NeuroImage Clinical 18: 720-729. DOI: 10.1016/j.nicl.2018.03.006
  • Schlemm E*, Cheng B*, Fischer F, Hilgetag C, Gerloff C, Thomalla G (2017) Altered topology of structural brain networks in patients with Gilles de la Tourette syndrome. Sci Rep 7: 10606. DOI: 10.1038/s41598-017-10920-y  (* shared authorship)
  • Boenstrup M, Schulz R, Feldheim J, Hummel FC, Gerloff C (2016) Dynamic causal modelling of EEG and fMRI to characterize network architectures in a simple motor task. Neuroimage 124(Pt A): 498-508. DOI: 10.1016/j.neuroimage.2015.08.052
  • Schulz R, Buchholz A, Frey B, Bönstrup M, Cheng B, Thomalla G, Hummel F, Gerloff C (2016) Enhanced effective connectivity between primary motor cortex and intraparietal sulcus in well-recovered stroke patients. Stroke 47: 482-489. DOI: 10.1161/STROKEAHA.115.011641

  • Boenstrup M*, Schulz R*, Cheng B, Feldheim J, Zimerman M, Thomalla G, Hummel FC, Gerloff C (2015) Evolution of brain activation after stroke in a constant-effort versus constant-output motor task. Restor Neurol Neurosci 33: 845-864. DOI: 10.3233/RNN-150527 (* shared authorship)
  • Cheng B, Schulz R, Bönstrup M, Hummel FC, Gerloff C, Fiehler J, Sedlacik J, Thomalla G (2015) Structural plasticity of remote cortical brain regions is determined by connectivity to the primary lesion in subcortical stroke. J Cereb Blood Flow Metab 35: 1507-1514. DOI: 10.1038/jcbfm.2015.74
  • Boelmans K, Spies L, Sedlacik J, Fiehler J, Jahn H, Gerloff C, Münchau A (2014) A novel computerized algorithm to detect microstructural brainstem pathology in Parkinson’s disease using standard 3 Tesla MR imaging. J Neurol 261: 1968-1975. DOI: 10.1007/s00415-014-7440-6
  • Cheng B, Forkert ND, Zavaglia M, Hilgetag CC, Golsari A, Siemonsen S, Fiehler J, Pedraza S, Puig J, Hee Cho T-H, Alawneh J, Baron J-C, Ostergaard L, Gerloff C, Thomalla G, (2014) Influence of stroke infarct location on functional outcome measured by the modified rankin scale. Stroke 45: 1695-1702. DOI: 10.1161/STROKEAHA.114.005152
  • Heise K, Niehoff M, Feldheim J, Liuzzi G, Gerloff C, Hummel FC (2014) Differential behavioral and physiological effects of anodal transcranial direct current stimulation in healthy adults of younger and older age. Front Aging Neurosci 6:146. DOI: 10.3389/fnagi.2014.00146
  • Heise KF, Zimerman M, Hoppe J, Gerloff C, Wegscheider K, Hummel FC (2013) The Aging Motor System as a Model for Plastic Changes of GABA-Mediated Intracortical Inhibition and Their Behavioral Relevance. J Neurosci 33: 9039-9049. DOI: 10.1523/JNEUROSCI.4094-12.2013

Project C2

  • Cheng B, Chen J, Königsberg A, Mayer C, Rimmele D L, Patil K R, Gerloff C, Thomalla G, Eickhoff S B (2023) Mapping the deficit dimension structure of the National Institutes of Health Stroke Scale. Ebiomedicine 87: 104425. DOI: 10.1016/j.ebiom.2022.104425
  • Frey BM, Shenas F, Boutitie F, Cheng B, Cho TH, Ebinger M, Endres M, Fiebach JB, Fiehler J, Galinovic I, Barow E, Königsberg A, Schlemm E, Pedraza S, Lemmens R, Thijs V, Muir KW, Nighoghossian N, Simonsen CZ, Gerloff C, Thomalla G (2023) Intravenous thrombolysis in patients with white matter hyperintensities in the WAKE-UP Trial. Stroke. 54: 1718-1725. DOI: 10.1161/STROKEAHA.122.040247
  • Mayer C, Nägele FL, Petersen M, Schell M, Aarabi G, Beikler T, Borof K, Frey BM, Nikorowitsch J, Senftiger J, Walther C, Jan-Wenzel JP, Zyriax BC, Bastian Cheng B, Thomalla G (2023) Association between coffee consumption and brain MRI pa-rameters in the Hamburg City Health Study. Nutrients 15: 674. DOI: 10.3390/nu15030674
  • Petersen M, Nägele FL, Mayer C, Schell M, Petersen E, Kühn S, Gallinat J, Fiehler J, Pasternak O, Matschke J, Glatzel M, Twerenbold R, Gerloff C, Thomalla G, Cheng B (2023) Brain imaging and neuropsychological assessment of individuals recovered from a mild to moderate SARS-CoV-2 infection Proc Natl Acad Sci USA 120: e2217232120. DOI: 101073/pnas2217232120
  • Schlemm E, Cheng B, Thomalla G, Kessner SS (2023) Functional lesion network mapping of sensory deficits after ischemic stroke. Stroke 54: 2918-2922. DOI: 10.1161/STROKEAHA.123.044470
  • Fischer F, Malherbe C, Schlemm E, Schröder J, Heinze M, Cheng B, Schulz M, Fiehler J, Larena-Avellaneda A, Gerloff C, Thomalla G  (2022) Intrinsic functional brain connectivity is resilient to chronic hypoperfusion caused by unilateral carotid artery stenosis. NeuroImage Clinical 34: 103014. DOI: 10.1016/j.nicl.2022.103014
  • Mayer C, Nägele FL, Petersen M, Frey BM, Hanning U, Pasternak O, Petersen E, Gerloff C, Thomalla G, Cheng B (2022) Free-water diffusion MRI detects structural alterations surrounding white matter hyperintensities in the early stage of cerebral small vessel disease. J Cerbr Blood Flow Met 42: 1707-1718. DOI: 10.1177/0271678X221093579
  • Petersen M, Frey BM, Mayer C, Kühn S, Gallinat J, Hanning U, Fiehler J, Borof K, Jagodzinski A, Gerloff C, Thomalla G, Cheng B (2022) Fixel based analysis of white matter alterations in early stage cerebral small vessel disease. SciRep 12: 1581. DOI: 10.1038/s41598-022-05665-2
  • Petersen M, Nägele FL, Mayer C, Schell M, Rimmele DL, Petersen E, Kühn S, Gallinat J, Hanning U, Fiehler J, Twerenbold R, Gerloff C, Thomalla G, Cheng B (2022) Brain network architecture constrains age-related cortical thinning. Neuroimage 264: 119721. DOI: 10.1016/jneuroimage2022119721
  • Schlemm E, Frey BM, Mayer C, Petersen M, Fiehler J, Hanning U, Kühn S, Twerenbold R, Gallinat J, Gerloff C, Thomalla G, Cheng B (2022) Equalization of brain state occupancy accompanies cognitive impairment in cerebral small vessel disease. Biol Psychiatry 92: 592-602. DOI: 10.1016/jbiopsych202203019
  • Schlemm E, Jensen M, Kuceyeski A, Jamison K, Ingwersen T, Mayer C, Königsberg A, Boutitie F, Ebinger M, Endres M, Fiebach J B, Fiehler J, Galinovic I, Lemmens R, Muir K W, Nighoghossian N, Pedraza S, Puig J, Simonsen CZ, Cheng B (2022) Early effect of thrombolysis on structural brain network organisation after anterior‐circulation stroke in the randomized WAKE‐UP trial. Hum Brain Mapp 43: 5053-5065. DOI: 10.1002/hbm.26073
  • Schulz M, Mayer C, Schlemm E, Frey BM, Malherbe C, Petersen M, Gallinat J, Kühn S, Fiehler J, Hanning U, Twerenbold R, Gerloff C, Cheng B, Thomalla G (2022) Association of age and structural brain changes with functional connectivity and executive function in a middle-aged to older population-based cohort. Front Aging Neurosci 14: 782738. DOI: 10.3389/fnagi2022782738
  • Cheng B, Petersen M, Schulz R, Boenstrup M, Krawinkel L, Gerloff C, Thomalla G (2021) White matter degeneration revealed by fiber-specific analysis relates to recovery of hand function after stroke. Hum Brain Mapp 42: 5423-5432. DOI: 10.1002/hbm25632
  • Crespo Pimentel B, Sedlacik J, Schröder J, Heinze M, Østergaard L, Fiehler J, Gerloff C, Thomalla G, Cheng B (2021) Comprehensive evaluation of cerebral hemodynamics and oxygen metabolism in revascularization of asymptomatic high-grade carotid stenosis. Clin Neuroradiol 32: 163-173. DOI: 10.1007/s00062-021-01077-3
  • Frey BM*, Petersen M*, Schlemm E, Mayer C, Hanning U, Engelke K, Fiehler J, Borof K, Jagodzinski A, Gerloff C, Thomalla G, Cheng B (2021) White matter integrity and structural brain network topology in cerebral small vessel disease: The Hamburg city health study. Hum Brain Mapp 42: 1406-1415. DOI: 10.1002/hbm.25301 (*shared authorship)
  • Kessner SS*, Schlemm E*, Gerloff C , Thomalla G , Cheng B (2021) Grey and white matter network disruption is associated with sensory deficits after stroke. NeuroImage Cinical, published online DOI: 10.1016/j.nicl.2021.102698 (*shared authorship)
  • Schlemm E, Ingwersen T, Königsberg A, Boutitie F, Ebinger M, Endres M, Fiebach J B, Fiehler J, Galinovic I, Lemmens R, Muir K W, Nighoghossian N, Pedraza S, Puig J, Simonsen C Z, Thijs V N, Wouters A, Gerloff C, Thomalla G, Cheng B (2021) Preserved structural connectivity mediates the clinical effect of thrombolysis in patients with anterior-circulation stroke. Nat Commun 12: 2590. DOI: 10.1038/s41467-021-22786-w
  • Mayer C, Frey BM, Schlemm E, Petersen M, Engelke K, Hanning U, Jagodzinski A, Borof K, Fiehler J, Gerloff C, Thomalla G, Cheng B (2020) Linking cortical atrophy to white matter hyperintensities of presumed vascular origin. J Cereb Blood Flow Metab 41: 1682-1691. DOI: 10.1177/0271678X20974170

  • Rimmele DL*, Frey BM*, Cheng B, Schulz R, Krawinkel LA, Bönstrup M, Hanna Braass H, Gerloff C, Thomalla G (2018) Association of extrapyramidal tracts’ integrity with performance in fine motor skills after stroke. Stroke 1: 1161. DOI: 10.1161/STROKEAHA.118.022706 (* shared authorship)
  • Stellmann JP, Hodecker S, Cheng B, Wanke N, Young KL, Hilgetag C, Gerloff C, Heesen C, Thomalla G, Siemonsen S (2017) Reduced rich-club connectivity is related to disability in primary progressive MS. Neurol Neuroimmunol Neuroinflamm 4: e375. DOI: 10.1212/NXI.0000000000000375
  • Meyer S*, Kessner SS*, Cheng B, Bonstrup, M, Schulz R, Hummel FC, De Bruyn N, Peeters A, Van Pesch V, Duprez T, Sunaert S, Schrooten M, Feys H, Gerloff C, Thomalla G, Thijs V, Verheyden G (2016) Voxel-based lesion-symptom mapping of stroke lesions underlying  somatosensory deficits. Neuroimage Clin 10: 257-266. DOI: 10.1016/j.nicl.2015.12.005 (* shared authorship)

  • Forkert ND, Cheng B, Kemmling A, Thomalla G, Fiehler J (2014) ANTONIA Perfusion and Stroke. A Software Tool for the Multi-purpose Analysis of MR Perfusion-weighted Datasets and Quantitative Ischemic Stroke Assessment. Methods Inf Med 53: 469-481. DOI: 10.3414/ME14-01-0007
  • Kaesemann P, Thomalla G, Cheng B, Treszl A, Fiehler J, Forkert ND (2014) Impact of severe extracranial ICA stenosis on MRI perfusion and diffusion parameters in acute ischemic stroke. Front Neurol 5: 254. DOI: 10.3389/fneur.2014.00254
  • Cheng B, Braass H, Ganos C, Treszl A, Biermann-Ruben K, Hummel FC, Müller-Vahl K, Schnitzler A, Gerloff C, Münchau A, Thomalla G (2013) Altered intrahemispheric structural connectivity in Gilles de la Tourette syndrome. NeuroImage Clinical 4: 174-181. DOI: 10.1016/j.nicl.2013.11.011
  • Forkert ND, Kaesemann P, Treszl A, Siemonsen S, Cheng B, Handels H, Fiehler J, Thomalla G (2013) Comparison of 10 TTP and Tmax Estimation Techniques for MR Perfusion-Diffusion Mismatch Quantification in Acute Stroke. Am J Neuroradiol 34: 1697-1703. DOI: 10.3174/ajnr.A3460

Project C4

  • Schulz R, Runge CG, Bönstrup M, Cheng B, Gerloff C, Thomalla G, Hummel FC (2019) Prefrontal-premotor pathways and motor output in well-recovered stroke patients. FrontNeurol 10: 105. DOI: 10.3389/fneur.2019.0010
  • Schulz R*, Frey B*, Koch P, Zimerman M, Bönstrup M, Feldheim J, Timmermann JE, Schön G, Cheng B, Thomalla G, Gerloff C, Hummel FC (2017) Cortico-cerebellar structural connectivity is related to residual motor output in chronic stroke. Cereb Cortex 27: 635-645. DOI: 10.1093/cercor/bhv251 (* shared authorship)
  • Backhaus W, Braass H, Renne T, Gerloff C, Humme FC (2016) Motor performance is not enhanced by daytime naps in older adults. Front Aging Neurosci 8: 125. DOI: 10.3389/fnagi.2016.00125
  • Koch P*, Schulz R*, Hummel FC (2016) Structural connectivity analyses in motor recovery research after stroke. Ann of Clin Trans Neurol 3: 233–244. DOI: 10.1002/acn3.278 (* shared authorship)
  • Quandt F, Boenstrup M, Schulz R, Jan E. Timmermann JE, Zimerman M, Nolte G, Hummel FC (2016) Spectral variability in the aged brain during fine motor control. Front Aging Neurosci 8: 305. DOI: 10.3389/fnagi.2016.00305

  • Wessel M*, Zimerman M*, Timmermann J, Heise K, Gerloff C, Hummel FC (2016) Enhancing consolidation of a new temporal motor skill by cerebellar noninvasive stimulation. Cereb Cortex 26: 1660-1667. DOI: 10.1093/cercor/bhu335 (* shared authorship)
  • Backhaus W, Kempe S, Hummel FC (2015) The effect of sleep on motor learning in the aging and stroke population – a systematic review. Restor Neurol Neurosci. 34: 153-164. DOI: 10.3233/RNN-150521
  • Bönstrup M*, Hagemann J*, Gerloff C, Sauseng P, Hummel FC (2015) Alpha oscillatory correlates of motor inhibition in the aged brain. Front Aging Neurosci 7: 193. DOI: 10.3389/fnagi.2015.00193  (* shared authorship)
  • Freundlieb N, Backhaus W, Brüggemann N, Gerloff C, Klein C, Pinnschmidt HO, Hummel FC (2015) Differential effects of BDNF val66met in repetitive associative learning paradigms. Neurobiol Learn Mem 123: 11-17. DOI: 10.1016/j.nlm.2015.04.010
  • Schulz R, Braass H, Liuzzi G, Hoerniss V, Lechner P, Christian Gerloff C, Hummel FC (2015) White matter integrity of premotor-motor connections is associated with motor output in chronic stroke patients. NeuroImage Clinical 7: 82–86. DOI: 10.1016/j.nicl.2014.11.006
  • Schulz R, Koch P, Zimerman M, Wessel M, Boenstrup M, Thomalla G, Cheng B, Gerloff C, Hummel FC (2015) Parietofrontal motor pathways and their association with motor function after stroke. Brain 138: 1949-1960. DOI: 10.1093/brain/awv100
  • Schulz R, Wessel MJ, Zimerman M, Timmerman J, Gerloff C and Hummel FC (2015) White matter integrity of specific dentato-thalamo-cortical pathways is associated with learning gains in precise movement timing. Cerebral Cortex 25: 1707-1714. DOI: 10.1093/cercor/bht356
  • Wessel MJ, Zimerman M, Hummel FC (2015) Non-invasive brain stimulation: an interventional tool for enhancing behavioral training after stroke. Front Hum Neurosci. 9: 265. DOI: 10.3389/fnhum.2015.00265
  • Zimerman M, Wessel MJ, Timmermann JE, Granström S, Gerloff C, Mautner VF, Hummel FC (2015) Impairment of procedural learning and motor intracortical inhibition in neurofibromatosis type 1 patients. EBioMedicine 2: 1430-1437. DOI: 10.1016/j.ebiom.2015.08.036
  • Berger B, Minarik T, Liuzzi GP, Hummel FC, Sauseng P (2014) EEG oscillatory phase-dependent markers for cortico-spinal excitability in the resting brain. BioMed Research International 2014: 936096. DOI: 10.1155/2014/936096
  • Boenstrup M, Feldheim J,  Heise K, Gerloff C, Hummel FC (2014) The control of complex finger movements by directional information flow between mesial frontocentral areas and the primary motor cortex. Eur J Neurosci 40: 2888-2897. DOI: 10.1111/ejn.12657
  • Schulz R*, Zimerman M*, Timmermann J, Wessel MJ, Gerloff C, Hummel FC (2014) White matter integrity of motor connections related to training gains in healthy aging. Neurobiology of Aging 35: 1404-1411. DOI: 10.1016/j.neurobiolaging.2013.11.024  (* shared authorship)
  • Zimerman M, Heise KF, Gerloff C, Cohen LG, Hummel FC (2014) Disrupting the ipsilateral motor cortex interferes with training of a complex motor task in older adults. Cereb Cortex 24: 1030-1036. DOI: 10.1093/cercor/bhs385
  • Zimerman M, Nitsch M, Giraux P, Gerloff C, Cohen LG, Hummel FC (2013) Neuroenhancement of the aging brain: restoring skill acquisition in old subjects. Ann Neurol 73: 10-15. DOI: 10.1002/ana.23761
  • Schulz R, Park CH, Boudrias MH, Gerloff C, Hummel FC, Ward NS (2012) Assessing the integrity of corticospinal pathways from primary and secondary cortical motor areas after stroke. Stroke 43: 2248-2251. DOI: 10.1161/STROKEAHA.112.662619
  • Zimerman M, Heise KF, Hoppe J, Cohen LG, Gerloff C, Hummel FC (2012) Modulation of training by single-session transcranial direct current stimulation to the intact motor cortex enhances motor skill acquisition of the paretic hand. Stroke 43: 2185-2191. DOI: 10.1161/STROKEAHA.111.645382

Project C5

  • Becker LF, Tunc S, Murphy P, Bäumer T, Weissbach A, Pauly MG, Al-Shorafat DM, Saranza G, Lang AE, Beste C, Donner TH, Verrel J, Münchau A (2022) Time estimation and arousal responses in dopa-responsive dystonia. Sci Rep 12: 14279. DOI: 10.1038/s41598-022-17545-w
  • Herzog R, Berger TM, Pauly MG, Xue H, Rueckert E, Münchau A, Bäumer T, Weissbach A (2022) Cerebellar transcranial current stimulation – an intraindividual comparison of different techniques. Front Neurosci 16: 987472. DOI: 10.3389/fnins.2022.987472
  • Pauly MG, Barlage M, Hamami F, Steinhardt J, Baarbé J, Tran S, Hanssen H, Herzog R, Tadic V, Brüggemann N, Chen R, Münchau A, Bäumer T, Weissbach A (2022) Subthalamic nucleus conditioning reduces premotor-motor interaction in Parkinson’s disease. Parkinsonism Relat Disord 96:6-12. DOI: 10.1016/j.parkreldis.2022.01.014
  • Steinhardt J, Hanssen H, Heldmann M, Neumann A, Münchau A, Schramm P, Rasche D, Saryyeva A, Büntjen L, Voges J, Tronnier V, Krauss JK, Münte TF, Brüggemann N (2022) Sweets for my sweet: modulation of the limbic system drives salience for sweet foods after deep brain stimulation in Parkinson’s disease. J Neurol Neurosurg Psychiatry 93: 324-331. DOI: 10.1136/jnnp-2021-326280
  • Steinhardt J, Hanssen H, Heldmann M, Sprenger A, Laabs B-H, Domingo A, Reyes CJ, Prasuhn J, Brand M, Rosales R, Münte TF, Klein C, Westenberger A, Oropilla JQ, Diesta C, Brüggemann N (2022) Prodromal X-linked dystonia-Parkinsonism is characterized by a subclinical motor phenotype. Mov Disord 37: 1474-1482. DOI: 10.1002/mds.29033
  • Weissbach A, Pauly MG, Herzog R, Hahn L, Halmans S, Hamami F, Bolte C, Camargos S, Jeon B, Kurian MA, Opladen T, Brüggemann N, Huppertz H-J, König IR, Klein C, Lohmann K (2022a) Relationship of genotype, phenotype, and treatment in dopa-responsive dystonia: MDSGene Review. Mov Disord 37: 237-252. DOI: 10.1002/mds.28874
  • Weissbach A, Steinmeier A, Pauly MG, Al-Shorafat DM, Saranza G, Lang A, Brüggemann N, Tadic V, Klein C, Münchau A, Bäumer T, Brown MJN (2022b) Longitudinal evaluations of somatosensory-motor inhibition in Dopa-responsive dystonia. Parkinsonism Relat Disord 95: 40-46. DOI: 10.1016/j.parkreldis.2021.12.016
  • Herzog R, Weissbach A, Bäumer T, Münchau A (2021) Complex dystonias: an update on diagnosis and care. J Neural Transm 128: 431-445. DOI: 10.1007/s00702-020-02275-y
  • Pauly MG, Steinmeier A, Bolte C, Hamami F, Tzvi E, Münchau A, Bäumer T, Weissbach A (2021) Cerebellar rTMS and PAS effectively induce cerebellar plasticity. Sci Rep 11: 3070. DOI: 10.1038/s41598-021-82496-7
  • Weissbach A, Steinmeier A, Pauly MG, Al-Shorafat DM, Saranza G, Lang AE, Brüggemann N, Tadic V, Klein C, Lohmann K, Brown MJN, Beste C, Münchau A, Bäumer T (2021) Multimodal longitudinal neurophysiological investigations in dopa-responsive dystonia. Mov Disord 36: 1986-1987. DOI: 10.1002/mds.28679
  • Brown MJN, Weissbach A, Pauly MG, Vesia M, Gunraj C, Baarbé J, Münchau A, Bäumer T, Chen R (2019) Somatosensory-motor cortex interactions measured using dual-site transcranial magnetic stimulation. Brain Stimul 12: 1229-1243. DOI: 10.1016/j.brs.2019.04.009
  • Brüggemann N, Domingo A, Rasche D, Moll CKE, Rosales RL, Jamora RDG, Hanssen H, Münchau A, Graf J, Weissbach A, Tadic V, Diesta CC, Volkmann J, Kühn A, Münte TF, Tronnier V, Klein C (2019) Association of pallidal neurostimulation and outcome predictors with X-linked dystonia Parkinsonism. JAMA Neurol 76: 211-216. DOI: 10.1001/jamaneurol.2018.3777
  • Tunc S, Baginski N, Lubs J, Bally JF, Weissbach A, Baaske MK, Tadic V, Brüggemann N, Bäumer T, Beste C, Münchau A (2019) Predictive coding and adaptive behavior in patients with genetically determined cerebellar ataxia–A neurophysiology study. Neuroimage Clin 24: 102043. DOI: 10.1016/j.nicl.2019.102043
  • Weissbach A, Udupa K, Ni Z, Gunraj C, Rinchon C, Baarbe J, Fasano A, Munhoz RP, Lang A, Tadic V, Brüggemann N, Münchau A, Bäumer T, Chen R (2019) Single-pulse subthalamic deep brain stimulation reduces premotor-motor facilitation in Parkinson’s disease. Parkinsonism Relat Disord 66: 224-227. DOI: 10.1016/j.parkreldis.2019.08.003
  • Westenberger A et al. (2019) A hexanucleotide repeat modifies expressivity of X-linked dystonia parkinsonism. Ann Neurol 85: 812–822. DOI: 10.1002/ana.25488

  • Beste C, Moll CKE, Pötter-Nerger M, Münchau A (2018) Striatal microstructure and its relevance for cognitive control. Trends Cog Sci 22: 747–751. DOI: 10.1016/j.tics.2018.06.007
  • Beste C, Mückschel M, Rosales R, Domingo A, Lee L, Ng, A, Klein C, Münchau A. (2018) The basal ganglia striosomes affect the modulation of conflicts by subliminal information-evidence from X-linked dystonia parkinsonism. Cereb Cortex 28: 2243-2252. DOI: 10.1093/cercor/bhx125
  • Zittel S, Tadic V, Moll CKE, Bäumer T, Fellbrich A, Gulberti A, Rasche D, Brüggemann N, Tronnier V, Münchau A (2018) Prospective evaluation of Globus pallidus internus deep brain stimulation in Huntington’s disease. Parkinsonism Relat Disord pii: S1353-8020(18)30080-4. DOI: 10.1016/j.parkreldis.2018.02.030
  • Beste C, Mückschel M, Rosales R, Domingo A, Lee L, Ng A, Klein C, Münchau A (2017) Dysfunctions in striatal microstructure can enhance perceptual decision making through deficits in predictive coding. Brain Struct Funct 222: 3807-3817. DOI: 10.1007/s00429-017-1435-x
  • Beste C, Mückschel M, Rosales R, Domingo A, Lee L, Ng A, Klein C, Münchau A (2017) Striosomal dysfunction affects behavioral adaptation but not impulsivity-Evidence from X-linked dystonia-parkinsonism. Mov Disord 32: 576-584. DOI: 10.1002/mds.26895
  • Brüggemann N, Rosales RL, Waugh JL, Blood AJ, Domingo A, Heldmann M, Jamora RD, Münchau A, Münte TF, Lee LV, Buchmann I, Klein C (2017) Striatal dysfunction in X-linked dystonia-parkinsonism is associated with disease progression. Eur J Neurol 24: 680-686. DOI: 10.1111/ene.13256
  • Tunc S, Brüggemann N, Baaske MK, Hartmann C, Grütz K, Westenberger A, Klein A, Münchau A, Bäumer T (2017) Facial twitches in ADCY5-associated disease – Myokymia or myoclonus? An electromyography study. Park Relat Disord 40: 73-75. DOI: 10.1016/j.parkreldis.2017.04.013
  • Weissbach A, Bäumer T, Pramstaller PP, Brüggemann N, Tadic V, Chen R, Klein C, Münchau A (2017) Abnormal premotor–motor interaction in heterozygous Parkin- and Pink1 mutation carriers. Clin Neurophysiol 128: 275-280. DOI: 10.1016/j.clinph.2016.10.007
  • Weissbach A, König IR, Hückelheim K, Pramstaller PP, Werner E, Brüggemann N, Tadic V, Lohmann K, Bäumer T, Münchau A, Kasten M, Klein C (2017) Influence of L-dopa on subtle motor signs in heterozygous Parkin- and PINK1 mutation carriers. Parkinsonism Relat Disord 42: 95-99. DOI: 10.1016/j.parkreldis.2017.07.003
  • Weissbach, A., Werner, E., Bally, J. F., Tunc, S., Löns, S., Timmann, D., Zeuner, K. E., Tadic, V., Brüggemann, N., Lang, A., Klein, C., Münchau, A., & Bäumer, T. (2017). Alcohol improves cerebellar learning deficit in myoclonus-dystonia: A clinical and electrophysiological investigation. Ann Neurol 82: 543-553. DOI: 10.1002/ana.25035

  • Tronnier VM, Domingo A, Moll CK, Rasche D, Mohr C, Rosales R, Capetian P, Jamora RD, Lee LV, Münchau A, Diesta CC, Tadic V, Klein C, Brüggemann N, Moser A (2015) Biochemical mechanisms of pallidal deep brain stimulation in X-linked dystonia parkinsonism. Parkinsonism Relat Disord 21: 954-959. DOI: 10.1016/j.parkreldis.2015.06.010
  • Weissbach A, Bäumer T, Brüggemann N, Tadic V, Zittel S, Cheng B, Thomalla G, Klein C, Münchau A (2015) Premotor-motor excitability is altered in dopa-responsive dystonia. Mov Disord, 30: 1705-1709. DOI: 10.1002/mds.26365 
  • Weissbach A, Bäumer T, Rosales R, Lee L, Brüggemann N, Domingo A, Westenberger A, Jamora R, Diesta CC, Brandt V, Tadic V, Zittel S, Klein C, Münchau A (2015) Neurophysiological fingerprints of X-linked dystonia-parkinsonism: A model basal ganglia disease. Mov Disord 30: 873-875. DOI: 10.1002/mds.26224
  • Zittel S, Heinbokel C, van der Vegt JP, Niessen E, Buhmann C, Gerloff C, Siebner HR, Münchau A,  Bäumer T (2015) Effects of dopaminergic treatment on functional cortico-cortical connectivity in Parkinson’s disease. Exp Brain Res 233: 329-337. DOI: 10.1007/s00221-014-4115-6 
  • Mencacci NE, Isaias IU, Reich MM, Ganos C, Plagnol V, Polke JM, Bras J, Hersheson J, Stamelou M, Pittman A, Noyce AJ, Mok KJ, Opladen T, Kunstmann E, Sidle K, Sweeney MG,  Houlden H, Hodecker S, Batla A, Münchau A, Volkmann J, Samnick S, Zecchinelli AL,  Pezzoli G, Marotta G, Lees A, Alegria P, Krack P, Cormier F, Lesage S, Brice A, Heutink P, Gasser T, Lubbe SJ, Morris HR, Majounie E, Gibbs R, Singleton A, Hardy J, Klebe S, Bhatia KP, Wood NW, for the International Parkinson’s Disease Genomics Consortium and UCL-exomes consortium (2014) Parkinson disease in GTP cyclohydrolase-1 mutation carriers. Brain 137: 2480-2492. DOI: 10.1093/brain/awu179
  • Weissbach A, Klein C (2014) Hereditary dystonia and parkinsonism: two sides of the same coin? Brain 137:2402-2404. DOI: 10.1093/brain/awu181
  • Groppa S, Schlaak BH, Münchau A, Werner-Petroll N, Dünnweber J, Bäumer T, van Nuenen BF, Siebner HR (2012) The human dorsal premotor cortex facilitates the excitability of ipsilateral primary motor cortex via a short latency cortico-cortical route. Hum Brain Mapp. 33: 419-30. DOI: 10.1002/hbm.21221
  • Klein C, Lohmann K, Ziegler A (2012) The Promise and Limitations of Genome-wide Association Studies. JAMA 8: 1-2

Project C6

  • Haaf M, Curic S, Rauh J, Steinmann S, Mulert C, Leicht G (2023) Opposite Modulation of the NMDA Receptor by Glycine and S-Ketamine and the Effects on Resting State EEG Gamma Activity: New Insights into the Glutamate Hypothesis of Schizophrenia. Int J Mol Sci 24: 1913. DOI: 10.3390/ijms24031913
  • Langhein M, Lyall AE, Steinmann S, Johanna Seitz-Holland J, Nägele F, Cetin-Karayumak S, Zhang F, Rauh J, Mußmann M, Billah T, Makris N, Pasternak O, O’Donnell LJ, Rathi Y, Leicht G, Kubicki M, Shenton ME, Mulert C (2023) The decoupling of structural and functional connectivity of auditory networks in individuals at clinical high-risk for psychosis. World J Biol Psychiatry 24: 387-399. DOI: 10.1080/15622975.2022.2112974
  • Haaf M, Curic S, Steinmann S, Rauh J, Leicht G, Mulert C (2022) Glycine attenuates impairments of stimulus-evoked gamma oscillations in the ketamine model of schizophrenia. Neuroimage 251: 119004. DOI: 10.1016/j.neuroimage.2022.119004
  • Curic S, Andreou C, Nolte G, Steinmann S, Thiebes S, Polomac N, Haaf M, Rauh J, Leicht G, Mulert C (2021) Ketamine alters functional gamma and theta resting-state connectivity in healthy humans: implications for schizophrenia treatment targeting the glutamate system. Front Psychiatry 12: 671007. DOI: 10.3389/fpsyt.2021.671007
  • Elyamany O, Leicht G, Herrmann CS, Mulert C (2021) Transcranial alternating current stimulation (tACS): from basic mechanisms towards first applications in psychiatry. Eur Arch Psychiatry Clin Neurosci 271: 135-156. DOI: 10.1007/s00406-020-01209-9
  • Leicht G, Björklund J, Vauth S, Mußmann M, Haaf M, Steinmann S, Rauh J, Mulert C (2021) Gamma-band synchronisation in a frontotemporal auditory information processing network. Neuroimage 239: 118307. DOI: 10.1016/j.neuroimage.2021.118307
  • Nägele FL, Pasternak O, Bitzan LV, Mußmann M, Rauh J, Kubicki M, Leicht G, Shenton ME, Lyall AE, Mulert C (2021) Cellular and extracellular white matter alterations indicate conversion to psychosis among individuals at clinical high-risk for psychosis. World J Biol Psychiartry 22: 214-227. DOI: 10.1080/15622975.2020.1775890
  • Schauer PA, Rauh J, Biedermann SV, Haaf M, Steinmann S, Leicht G, Mulert C (2021) Simultaneous EEG-fMRI reveals theta network alterations during reward feedback processing in borderline personality disorder. Sci Rep 11: 17336. DOI: 10.1038/s41598-021-96209-7
  • Steinmann S, Lyall AE, Langhein M, Nägele FL, Rauh J, Cetin-Karayumak S, Zhang F, Mussmann M, Billah T, Makris N, Pasternak O, O’Donnell LJ, Rathi Y, Kubicki M, Leicht G, Shenton ME, Mulert C (2021) Sex-related differences in white matter asymmetry and its implications for verbal working memory in psychosis high-risk state. Front Psychiatry 12: 686967. DOI: 10.3389/fpsyt.2021.686967
  • Leicht G, Andreou C, Nafe T, Nägele F, Rauh J, Curic S, Schauer P, Schöttle D, Steinmann S, Mulert C (2020) Alterations of oscillatory neuronal activity during reward processing in schizophrenia. J Psychiatr Res 129: 80-87. DOI: 10.1016/j.jpsychires.2020.05.031
  • Pedraz-Petrozzi B, Elyamany O, Rummel C, Mulert C (2020) Effects of inflammation on the kynurenine pathway in schizophrenia – a systematic review. J Neuroinflammation 17: 56. DOI: 10.1186/s12974-020-1721-z
  • Curic S, Leicht G, Thiebes S, Andreou C, Polomac N, Eichler I, Eichler L, Zöllner C, Gallinat J, Steinmann S, Mulert C (2019) Reduced auditory evoked gamma-band response and schizophrenia-like clinical symptoms under subanesthetic ketamine. Neuropsychopharmacology 44: 1239-1246. DOI: 10.1038/s41386-019-0328-5
  • Meier J, Nolte G, Schneider TR, Engel AK, Leicht G, Mulert C (2019) Intrinsic 40Hz-phase asymmetries predict tACS effects during conscious auditory perception. PLoS One 14: e0213996. DOI: 10.1371/journal.pone.0213996
  • Steinmann S, Leicht G, Mulert C (2019) The interhemispheric miscommunication theory of auditory verbal hallucinations in schizophrenia. Int J Psychophysiol 145: 83-90. DOI: 10.1016/j.ijpsycho.2019.02.002

  • Feroz FS, Leicht G, Mulert C (2019) The time course of dorsal and rostral-ventral anterior cingulate cortex activity in the emotional stroop experiment reveals valence and arousal aberrant modulation in patients with schizophrenia. Brain Topogr 32: 161-177. DOI: 10.1007/s10548-018-0677-0
  • Haaf M, Leicht G, Curic S, Mulert C (2018) Glutamatergic deficits in schizophrenia – biomarkers and pharmacological interventions within the ketamine model. Curr Pharm Biotechnol 19: 293-307. DOI: 10.2174/1389201019666180620112528
  • Steinmann S, Amselberg R, Cheng B, Thomalla G, Engel AK, Leicht G, Mulert C (2018) The role of functional and structural interhemispheric auditory connectivity for language lateralization – a combined EEG and DTI study. Scientific Reports 8: 15428. DOI: 10.1038/s41598-018-33586-6
  • Thiebes S, Steinmann S, Curic S, Polomac N, Andreou C, Eichler IC, Eichler L, Zöllner C, Gallinat J, Leicht G, Mulert C (2018) Alterations in interhemispheric gamma-band connectivity are related to the emergence of auditory verbal hallucinations in healthy subjects during NMDA-receptor blockade. Neuropsychopharmacology 3:1608-1615. DOI: 10.1038/s41386-018-0014-z
  • Andreou C*, Frielinghaus H*, Rauh J, Mußmann M, Vauth S, Braun P, Leicht G, Mulert C (2017) Theta- and high-beta networks for feedback processing: A simultaneous EEG-fMRI study in healthy male subjects. Transl Psychiatry 7: e1016. DOI: 10.1038/tp.2016.287 (* shared authorship)
  • Feroz FS, Leicht G, Steinmann S, Andreou C, Mulert C (2017) The time course of activity within the dorsal and rostral-ventral anterior cingulate cortex in the emotional stroop task. Brain Topogr 30: 30-45. DOI: 10.1007/s10548-016-0521-3
  • Konte B, Leicht G, Giegling I, Pogarell O, Karch S, Hartmann AM, Friedl M, Hegerl U, Rujescu D, Mulert C (2017) A genome-wide association study of early gamma-band response in a schizophrenia case–control sample. World J Biol Psychiatry 1-8. DOI: 10.1080/15622975.2017.1366054
  • Steinmann S, Leicht G, Andreou C, Polomac N, Mulert C (2017) Auditory verbal hallucinations related to altered long-range synchrony of gamma-band oscillations. Sci Rep 7:8401. DOI: 10.1038/s41598-017-09253-7
  • Thiebes S, Leicht G, Curic S, Steinmann S, Polomac N, Andreou C, Eichler I, Eichler L, Zöllner C, Gallinat J, Hanganu-Opatz I, Mulert C (2017) Glutamatergic deficit and schizophrenia-like negative symptoms: New evidence from ketamine-induced mismatch negativity alterations in healthy male humans. J Psychiatry Neurosci 42: 273-283. DOI: 10.1038/s41598-017-09253-7
  • Kornmayer L, Leicht G, Mulert C (2016) Attentional capture by physically salient stimuli in the gamma frequency is associated with schizophrenia symptoms. World J Biol Psychiatry 1-11. DOI: 10.1080/15622975.2016.1258491
  • Leicht G, Vauth S, Polomac N, Andreou C, Rauh J, Mußmann M, Karow A, Mulert C (2016) EEG-informed fMRI reveals a disturbed gamma-band specific network in subjects at high-risk for psychosis. Schizophr Bull 42: 239-249. DOI: 10.1093/schbul/sbv092

  • Leicht G, Andreou C, Polomac N, Lanig C, Schöttle D, Lambert M, Mulert C (2015) Reduced auditory evoked gamma band response and cognitive processing deficits in first episode schizophrenia. World J Biol Psychiatry 16: 1-11. DOI: 10.3109/15622975.2015.1017605
  • Polomac N, Leicht G, Nolte G, Andreou C, Schneider TR, Steinmann S, Engel AK, Mulert C (2015) Generators and connectivity of the early auditory evoked gamma band response. Brain Topogr 28: 865-878. DOI: 10.1007/s10548-015-0434-6
  • Wigand M, Kubicki M, Clemm von Hohenberg C, Leicht G, Karch S, Eckbo R, Pelavin PE, Hawley K, Rujescu D, Bouix S, Shenton ME, Mulert C (2015) Auditory verbal hallucinations and the interhemispheric auditory pathway in chronic schizophrenia. World J Biol Psychiatry 16: 31-44. DOI: 10.3109/15622975.2014.948063
  • Kornmayer L, Gregor Leicht G, Mulert C (2014) Increased Gamma Oscillations Evoked by Physically Salient Distracters are Associated with Schizotypy. Brain Topography 28: 153-161. DOI: 10.1007/s10548-014-0418-y
  • Steinmann S, Leicht G, Ertl M, Andreou C, Polomac N, Westerhausen R, Friederici AD, Mulert C (2014) Conscious auditory perception related to long-range synchrony of gamma oscillations. Neuroimage 100: 435-443. DOI: 10.1016/j.neuroimage.2014.06.012
  • Steinmann S, Leicht G, Mulert C (2014) Interhemispheric auditory connectivity: structure and function related to auditory verbal hallucinations. Front Hum Neurosci 8: 55. DOI: 10.3389/fnhum.2014.00055
  • Clemm von Hohenberg C, Wigand MC, Kubicki M, Leicht G, Giegling I, Karch S, Hartmann AM, Konte B, Friedl M, Ballinger T, Eckbo R, Bouix S, Jäger L, Shenton ME, Rujescu D, Mulert C (2013) CNTNAP2 polymorphisms and structural brain connectivity: A diffusion-tensor imaging study. J Psychiatr Res 47: 1349-1356. DOI: 10.1016/j.jpsychires.2013.07.002

Project C7

  • Schiwy LC, Forlim CG, Fischer DJ, Kühn S, Becker M, Gallinat J (2022) Aberrant functional connectivity within the salience network is related to cognitive deficits and disorganization in psychosis. Schizophr Res 246: 103-111. DOI: 10.1016/j.schres.2022.06.008
  • Kühn S, Forlim CG, Lender A, Wirtz J, Gallinat J (2021) Brain functional connectivity differs when viewing pictures from natural and built environments using fMRI resting state analysis. Sci Rep 11: 4110. DOI: 10.1038/s41598-021-83246-5
  • Forlim CG*, Klock L*, Bächle J, Stoll L, Giemsa P, Fuchs M, Schoofs N, Montag C, Gallinat J, Kühn S (2020) Reduced resting-state connectivity in the precuneus is correlated with apathy in patients with schizophrenia. Sci Rep 10: 2616. DOI: 10.1038/s41598-020-59393-6. *Shared first authorship
  • Salminen T*, Forlim CG*, Schubert T, Kühn S (2020) Dual n-back training improves functional connectivity of the right inferior frontal gyrus at rest. Sci Rep 10: 20379. DOI: 10.1038/s41598-020-77310-9. *Shared first authorship
  • Filevich E, Forlim CG, Fehrman C, Forster C, Paulus M, Shing YL, Kühn S (2020) I know that I know nothing: Cortical thickness and functional connectivity underlying meta-ignorance ability in pre-schoolers. Dev Cogn Neurosci. 41: 100738. DOI: 10.1016/j.dcn.2019.100738
  • Forlim CG, Bittner L, Mostajeran F, Steinicke F, Gallinat J, Kühn S (2019) Stereoscopic rendering via Goggles elicits higher functional connectivity during virtual reality gaming. Front Hum Neurosci 13: 365. DOI: 10.3389/fnhum.2019.00365
  • Forlim CG* & Finotteli P*, Dulio P, Klock L, Pini A, Bächle J, Giemsa P, Fuchs M, Schoofs N, Montag C, Stoll L, Gallinat J, Kühn S (2019) New graph-theoretical-multimodal approach using temporal and structural correlations reveal disruption in the thalamo-cortical network in patients with schizophrenia. Brain Connect 9: 760-769. DOI: 10.1089/brain.2018.0654. *Shared first authorship

  • Kühn S, Berna F, Lüdtke T, Gallinat J, Moritz S (2018) Fighting pepression: action video game play may reduce rumination and increase subjective and objective cognition in depressed patients. Frontiers in Psychology 9: 129. DOI: 10.3389/fpsyg.2018.00129
  • Kühn S, Kugler D, Schmalen K, Weichenberger M, Witt C, Gallinat J (2018) Does playing violent video games cause aggression? A longitudinal intervention study. Mol Psychiatry 24:1220-1234. DOI: 10.1038/s41380-018-0031-7
  • Kühn S, Kugler D, Schmalen K, Weichenberger M, Witt C, Gallinat J (2018) The myth of blunted gamers: No evidence for desensitization in empathy for pain after a violent video game intervention in a longitudinal fMRI study on non-gamers. Neurosignals 26: 22-30. DOI: 10.1159/000487217
  • Pallarés V*, Insabato A*, Sanjuán A, Kühn S, Mantini D, Deco G*, Gilson M* (2018) Extracting orthogonal subject- and condition-specific signatures from fMRI data using whole-brain effective connectivity. Neuroimage 178: 238-254. DOI: 10.1016/j.neuroimage.2018.04.070 (* shared authorship)
  • Finc K, Bonna K, Lewandowska M, Wolak T, Nikadon J, Dreszer J, Duch W, Kühn S (2017) Transition of the functional brain network related to increasing cognitive demands. Hum Brain Mapp, 38: 3659-3674. DOI: 10.1002/ hbm.23621
  • Weichenberger M, Bauer M, Kühler R, Hensel J, Forlim CG, Ihlenfeld A, Ittermann B, Gallinat J, Koch C, Kühn S (2017) Altered cortical and subcortical connectivity due to infrasound administered near the hearing threshold – evidence from fMRI. PloS One 12(4), e0174420. DOI: 10.1371/journal.pone.0174420

Project C8

  • Gülke E, Alsalem M, Kirsten M, Vettorazzi E, Choe C, Hidding U, Zittel S, Buhmann C, Schaper M, Gulberti A, Moll CKE, Hamel W, Johannes Koeppen J, Gerloff C, Pötter-Nerger M (2022) Comparison of Montreal cognitive assessment and Mattis dementia rating scale in the preoperative evaluation of subthalamic stimulation in Parkinson´s disease. PLOS one 17: e0265314. DOI: 10.1371/journal.pone.0265314
  • Hidding U, Schaper M, Gulberti A, Buhmann C, Gerloff C, Moll CKE, Hamel W, Choe CU, Pötter-Nerger M (2022) Short pulse and directional thalamic deep brain stimulation have differential effects in parkinsonian and essential tremor. Sci Rep 12: 7251. DOI: 10.1038/s41598-022-11291-9
  • Horn MA, Gulberti A, Hidding U, Gerloff C, Hamel W, Moll CKE, Pötter-Nerger M (2021) Comparison of Shod and Unshod Gait in Patients With Parkinson’s Disease With Subthalamic and Nigral Stimulation. Front Hum Neurosci 15:  751242. DOI:10.3389/fnhum.2021.751242
  • Seger A, Gulberti A, Vettorazzi E, Braa H, Buhmann C, Gerloff C, Hamel W, Moll CKE, Pötter-Nerger M (2021) Short Pulse and Conventional Deep Brain Stimulation Equally Improve the Parkinsonian Gait Disorder. J Parkinsons Dis 11: 1455-1464. DOI:10.3233/JPD-202492
  • Horn MA, Gulberti A, Gulke E, Buhmann C, Gerloff C, Moll CKE, Hamel W, Volkmann J, Pötter-Nerger M (2020) A New Stimulation Mode for Deep Brain Stimulation in Parkinson’s Disease: Theta Burst Stimulation. Mov Disord 35:  1471-1475. DOI:10.1002/mds.28083

  • Choe C-U*, Hidding U*, Schaper M, Gulberti A, Köppen J, Buhmann C, Gerloff C, Moll CKE, Hamel W, Pötter-Nerger M (2018) Thalamic short pulse stimulation diminishes adverse effects in essential tremor patients. Neurology 91: e704-e713. DOI: 10.1212/WNL.0000000000006033 (* shared authorship)
  • Sharott A, Gulberti A, Hamel W, Köppen JA, Münchau A, Buhmann C, Pötter-Nerger M, Westphal M, Gerloff C, Moll CKE*, Engel AK* (2018) Spatio-temporal dynamics of cortical drive to human subthalamic nucleus in Parkinson’s disease are topographically specific. Neurobiology of Disease 112: 49-62. DOI: 10.1016/j.nbd.2018.01.001 (* shared authorship)
  • Hidding U, Gulberti A. Horn A, Buhmann C, Hamel W, Koeppen JA, Westphal M, Engel AK, Gerloff C, Weiss D, Moll CK, Pötter-Nerger M (2017) Impact of combined subthalamic nucleus and substantia nigra stimulation on neuropsychiatric symptoms in Parkinson’s disease patients. Parkinsons Dis 2017: 7306192. DOI: 10.1155/2017/7306192
  • Pötter-Nerger M, Reese R, Steigerwald F, Heiden JA, Herzog J, Moll CKE, Hamel W, Ramirez-Pasos U, Falk D, Mehdorn M, Gerloff C, Deuschl G, Volkmann J (2017) Movement-related activity of human subthalamic neurons during a reach-to-grasp task. Front Hum Neurosci 11: 436. DOI: 10.3389/fnhum.2017.00436

  • Pötter-Nerger M, Volkmann J (2013) Deep brain stimulation for gait and postural symptoms in Parkinson’s disease. Mov Disord 28:  1609-15. DOI: 10.1002/mds.25677

Project C9

  • Schirner M, Deco D, Ritter P (2023) Learning how network structure shapes decision-making for bio-inspired computing. Nat Commun 14: 2963. DOI: 10.1038/s41467-023-38626-y
  • Schirner M, Domide L, Perdikis D, Triebkorn P, Stefanovski L, Pai R, Prodan P, Valean B, Palmer J, Langford C, Blickensdörfer A, van der Vlag M, Diaz-Pier S, Peyser A, Woodman M, Zehl L, Fousek J, Petkoski S, Kusch L, Hashemi M, Marinazzo D, Mangin J, Flöel A, Akintoye S, Stahl BC, Deco G, McIntosh AR, Hilgetag C, Morgan M, Schuller B, Upton A, McMurtrie C, Dickscheid T, Bjaalie J, Amunts K, Mersmann J, Jirsa V, Ritter P (2022) Brain simulation as a cloud service: The Virtual Brain on the European research platform EBRAINS. Neuroimage 251: 118973. DOI: 10.1016/j.neuroimage.2022.118973
  • Aerts H, Colenbier N, Almgren H, Dhollander T, JR Daparte, Clauw K, Johri A, Meier J, Palmer J, Schirner M, Ritter P, Marinazzo D (2022) Pre- and post-surgery tumor multimodal MRI data optimized for large-scale computational modeling. Sci Data 9: 676. DOI: 10.1038/s41597-022-01806-4
  • Chettouf S, Triebkorn P, Daffertshofer A, Ritter P (2022) Unimanual sensorimotor learning – a simultaneous EEG-fMRI study.  Hum Brain Mapp 43: 2348-2364. DOI: 10.1002/hbm.25791
  • Klingner C, Denker M, Grün S, Hanke M, Oelltze-Jafra P, Ohl F, Radny J, Rotter S, Scherberger HJ, Stein A, Wachtler T, Witte O, Ritter P (2022) Research data management and data sharing for reproducible research – results of a community survey of the German National Research Data Infrastructure Initiative Neuroscience. eNeuro 10: ENEURO.0215-22.2023. DOI: 10.1523/ENEURO.0215-22.2023
  • Meier J, Perdikis D, Blickensdörfer A, Stefanovski L, Liu Q, Maith O, Dinkelbach HÜ, Baladron J, Hamker F, Ritter P (2022) Virtual deep brain stimulation: multiscale co-simulation of spiking basal ganglia model and whole-brain mean-field model with The Virtual Brain. Exp Neurol 354: 114111. DOI: 10.1016/j.expneurol.2022.114111
  • Petkoski S, Ritter P, Jirsa VK (2022) White-matter degradation and dynamical compensation support age-related functional alterations in human brain. Cereb Cortex 22: 6241-6256. DOI:10.1093/cercor/bhac500
  • Schirner M, Kong X, Yeo BTT, Deco G, Ritter P (2022) Dynamic primitives of brain network interaction. Neuroimage 250: 118928. DOI: 10.1016/j.neuroimage.2022.118928
  • Stylianou O, Kaposzta Z, Czoch A, Stefanovski L, Yabluchanskiy A, Racz FS, Ritter P, Eke A, Mukli P (2022) Scale-free functional brain networks exhibit increased connectivity, are more integrated and less segregated in patients with Parkinson’s disease following dopaminergic treatment. Fractal Fract 6: 737. DOI: 10.3390/fractalfract6120737
  • Triebkorn P, Stefanovski L, Dhindsa K, Diaz-Cortes MA, Bey P, Bülau K, Pai R, Spiegler A, Jirsa V, McIntosh AR, Ritter P, for the Alzheimer’s Disease Neuroimaging Initaitive (2022) Brain simulation augments machine-learning-based classification of dementia. Alzheimers Dement 8: e12303. DOI: 10.1002/trc2.12303
  • Arabyazd L, Shen K, Wang Z, Hofmann-Apitiu Ms, Ritter P, McIntosh AR, Battaglia D, Jirsa V (2021) Virtual connectomic datasets in Alzheimer’s disease and aging using whole-brain network dynamics modeling. eNeuro 8: ENEURO.0475-20.2021. DOI: 10.1523/ENEURO.0475-20.2021
  • Good T, Schirner M, Shen K, Ritter P, Mukherjee P, Levine B, McIntosh AR (2021) Personalized connectome-based modeling in patients with semi-acute phase mild TBI: relationship to acute neuroimaging and 6-month follow-up. eNeuro 9: ENEURO.0075-21.2022. DOI: 10.1523/ENEURO.0075-21.2022
  • Stefanovski L, Meier J, Pai R, Triebkorn P, Lett T, Martin L, Bülau K, Hofmann-Apitius M, Solodkin A, McIntosh AR, Ritter P (2021) Bridging Scales in Alzheimer’s disease: biological framework for brain simulation with The Virtual Brain. Front Neuroinform 15: 630172. DOI: 10.3389/fninf.2021.630172
  • Aerts H, Schirner M, Dhollander T, Jeurissen B, Achten E, Van Roost D, Ritter P, Marinazzo D (2020) Modeling brain dynamics after tumor resection using The Virtual Brain. Neuroimage 213: 116738. DOI: 10.1016/j.neuroimage.2020.116738
  • Battaglia D, Boudou T, Hansen ECA, Chettouf S, Daffertshofer A, McIntosh AR, Zimmermann J, Ritter P*, Jirsa V* (2020) Functional connectivity dynamics of the resting state across the human adult lifespan. Neuroimage 222: 117156. DOI: 10.1016/j.neuroimage.2020.117156 (*Shared authorship)
  • Chettouf S, Rueda-Delgado LM, de Vries R, Ritter P, Daffertshofer A (2020) Are unimanual movements bilateral? Neurosci Biobehav Rev 113: 39-50. DOI: 10.1016/j.neubiorev.2020.03.002
  • Palesi F, Lorenzi RM, Casellato C, Ritter P, Jirsa V, Gandini Wheeler-Kingshott CAM, D’Angelo E (2020) The importance of cerebellar connectivity on simulated brain dynamics. Front Cell Neurosci 14: 240. DOI: 10.3389/fncel.2020.00240
  • Scheibe C, Neurmann WJ, Lange M, Scheel M, Furth C, Köhnlein M, Mergenthaler P, Schultze-Amberger J, Triebkorn P, Kühn A, Ritter P, Meisel A (2020) Movement disorders after hypoxic-ischemic encephalopathy following cardiac arrest in adults. Eur J Neurol 27: 1937-1947. DOI: 10.1111/ene.14326
  • Carpentier S, McCulloch A, Brown T, Ritter P, Wang Z, Salimpoor V, Shen K, McIntosh AR (2019) Complexity matching: brain signals mirror environment information patterns during music listening and reward. J Cogn Neurosci 32: 734-745. DOI: 10.1162/jocn_a_01508
  • Poldrack RA, Feingold F, Frank MJ, Gleeson P, de Hollander G, Huys QJM, Love BC, Markiewitcz CJ, Moran R, Ritter P, Turner BM, Yarkoni T, Zhang M, Cohen JD (2019) The importance of standards for sharing of computational models and data. Comput Brain Behav 2: 229-232. DOI: 10.1007/s42113-019-00062-x
  • Shen K, Bezgin G, Schirner M, Ritter P, Everling S, McIntosh AR (2019) A macaque connectome for large-scale network simulations in TheVirtualBrain. Sci Data 6: 123. DOI: 10.1038/s41597-019-0129-z
  • Stefanovski L, Triebkorn P, Spiegler A, Diaz-Cortes M, Solodkin A, Jirsa V, McIntosh AR, Ritter P, for the Alzheimer’s Disease Neuroimaging Initiative (2019) Linking molecular pathways and large-scale computational modeling to assess candidate disease mechanisms and pharmacodynamics in Alzheimer’s disease. Front Comput Neurosci 13: 54. DOI: 10.3389/fncom.2019.00054
  • Costa Klein P, Ettinger U, Schirner M, Ritter P, Rujescu D, Falkai P, Koutsouleris N, Kambeitz-Ilankovic L, Kambeitz J (2020) Brain network simulations indicate effects of neuregulin-1 genotype on excitation-inhibition balance in cortical dynamics. Cereb Cortex 31: 2013-2025. DOI: 10.1093/cercor/bhaa339